Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets

Common variable immunodeficiency (CVID) is increasingly recognized for its association with autoimmune and inflammatory complications.Despite recent advances in immunophenotypic and genetic discovery, clinical care of CVID remains limited by our inability to accurately model risk for non-infectious disease development.Herein, we demonstrate the uti

read more

Effect of Water Stress on Physiological and Morphological Leaf Traits: A Comparison among the Three Widely-Spread Invasive Alien Species Ailanthus altissima, Phytolacca americana, and Robinia pseudoacacia

Invasive alien species (IAS) are a problem, especially in drought-prone environments such as the Mediterranean Basin where the exacerbation of the already severe conditions could constrain the native species acclimatation degree, creating new opportunities for IAS.Climate change may drive IAS expansions, even if different IAS can vary in their accl

read more

A Study on Occupational Pain Among Dentists of Surat City

This study has been conducted to measure prevalence of pain related to dental work among dentists in Surat city and to identify the aggravating and relieving factors Snacks associated with the pain.In this cross sectional study, 77 randomly selected dentists were interviewed.Prevalence of pain was 63.6 percent.Back was the commonest site for pain.P

read more

Ambiguity drives higher-order Pavlovian learning.

In the natural world, stimulus-outcome associations are often ambiguous, and most associations are highly complex and situation-dependent.Learning to disambiguate these complex associations to identify which specific outcomes will occur in which situations is critical for survival.Pavlovian occasion setters are stimuli that determine Siemens ET651H

read more

Results from NEXT-D: the association of a pre-diabetes-specific health plan and rates of incident diabetes among a national sample of working-age adults

BackgroundPre-diabetes affects one-third of adults in the USA and a subset will progress to type 2 diabetes.Our objective was to determine whether a disease-specific health plan, known as the Diabetes Health Plan (DHP), designed to improve care for persons with pre-diabetes and diabetes also led to lower rates of incident diabetes among adults with

read more